Classes Of Radiopaque Contrast Media Biology Essay



In medical imaging, contrast media have been search because the differences in density among body tissues is too small. Contrast media is used to provide more adequate contrast for good visualization and differences of anatomical details. This will be advantages to radiographer to provide more clearly image that can be easily to anylize. It is necessary to increase or decrease density of interested organ to provide desired contrast. Because the use of computed tomography(CT), magnetic resonance imaging(MRI) and digital subtraction angiography(DSA) increase, the use of contrast media is also increase. Example procedures using contrast media is barium enemas and excretory urograms. In advance procedures they increase the region of interest density by addition of radiopaque substance that render organ opaque. However, in some situation density of organ can be decrease by addition of radiolucent substance. Amount of contrast media that being use are greater than those used for therapeutic drugs. This procedure is designed to make contrast media remain in organ of interest for very short period of time which not cause any changes biologically or chemically in the body.


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Contrast agents are classified into two group that depending on their interaction with x-ray radiation. Positive contrast agents that is radiopaque and negative contrast agents that is radiolucent.

There are four negative agents that always be used in medical imaging. That is the air, oxygen, carbon dioxide and nitrous oxide. This is the most commontly used as radiolucent contrast agents. Negative contrast agents are also used in conjuction with positive contrast agents. It known as common procedure double contrast barium enema. This negative contrast agents has it disadvantages that air and oxygen can cause gas emboli in certain procedure. However diffrently for carbon dioxide and nitrogen that not pose risk of gas emboli although it can be used with relatively safety. Moreover carbon dioxide and nitrogen able to be absorbed rapidly by the body. This is advantageous when rapid absorption is needed but not suitable in a cases when many radiographs are taken.

Positive contrast agents are use because they have high atomic number that can cause an increases in the attenuation of x-rays, thats why it is considered as radiopaque. It produce an area decreased radiographic density on the image receptor. Positive contrast agents that commonly used in radiographic procedure is iodine, bromine and barium. When this contrast agents is filled in organ, it will make that organ become radiopaque and image appears clear or white on radiograph (image receptor). It can be taken in form of liquids,tablets and powders also can be inserted to body through a variety of routes. This contrast are relatively nontoxic in most cases but certain patient may exhibit reactions of varying severity especially to agents containing iodine and in some cases small amount of these agents may cause death.

Classes Of Radiopaque Contrast Media

Osmolarity and osmolality refer to the osmotic pressure of a solution. Osmolarity refer to the concentration per volume of solution while osmolality refer to weight or milliosmols per kilogram of water.

The contrast agents used for intravenous injections has two major classes. That is ionic and non ionic. The ionic compounds are further subdivided into high osmolarity ionic compounds(HOCA) and low osmolality ionic compounds(LOCA) . All positive contrast agent used intravenous injection are organic iodine compound that use iodine as the substance that provides the contrast


Characteristic Of Radiopaque Contrast Media

Characteristics that important for radiopaque contrast agent is viscocity, toxicity, iodine content, miscibility and persistence. When contrast agent the iodine concentration increase, viscosity increase. More viscous cotrast agent need greater injection to send same amount of material then icrease possibilities of patient trauma and catheter damage.

The miscibility or immiscibility of contrast agent is important as angiographic contrast medium must completely miscibility with the blood to avoid any possibilities of contrast medium embolization.

Contast agent persistent in body is important. It was foreign substance that instilled into body organs. It more good that they can be excreted fastly from body but they must stay and concentratein the body organs for long enough to provide an adequate radiographic study.

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Selective localization has become more a part of the route of elimination of the substances rather than a means to get it to specific location. Mostly positive contrast agents eliminated through urinary system tha make blood urea nitrogen(BUN) and creatinine test is important. If urinary system is already stressed, additional load will caused some major patient reaction.

Exretory Pathways

Every contrast solution that being use has it elimination routes. The main routes used to eliminate positive contrast agents used in the vascular international studies are urinary system and hepatic portal system. Those agents that utilize the hepatic portal system are primarily used to study the organs associated with the sysem. The primarily route for the elimination of most of the organic iodide compounds is through the urinary system. So it is important to know the status of the kidney's ability to take this task before the examination. Patient must take both BUN and creatinine test to determine renal status. And results must be checked before doing the examination. Renal insufficiency is indicated if the BUN exceed 30mg/dl and creatinine is above 1.5mg/dl. Physician should be noticed regarding the results of these tests prior to the injection.

General Precautions

Before injection, patient must be inform about the procedure and its risk. Obtain an informed consent from the patient for precaution and establish a set of baseline vital sign for the pation for our reference.

Know the patient, by checking the chart for history of allergy or hypersensitivity to take care patient and avoid from any mistake. Make sure patient take a blood work test and checking the result of the patient's blood work before examination. Test of blood work is to investigate about blood urea nitrogen, creatinine, prothrombintime in cases of arterial access, partial thromboplastin time and platelet count.

Check whether patient has other medical problems about hepatic or renal disease, pregnancy, multiple myeloma, congestive heart failure, Graves' disease, Homozygosity for sickle cell disease, known or suspected pheochromocytoma(solid tumors of neurogenic origin), severe cardiovascular disease bronchial asthma, severe cardiovascular disease bronchial asthma and lastly Hyperthyroidism.

Know about the procedure of contraindications and limitations to the specific special procedure. Know the possibilities reaction that can occur with the contrast agent used. Checking the emergency equipment and know the location and contents of crash cart.

After injection we must know where physician may be reached. Evaluate patient's vital functions for abnormalities, respiration rate, pulse rate, blood pressure and presence of cyanosis. Must remain with and monitor the patient for at least 20 minutes after injection.


In this examination, approximately 70% reactions occur within 5 minutes of the injection. 16% will occur more than 5 minutes after injection ans lastly 14% occur 15 minutes after injection. So it is advisable to radiographer remain with patient at least 15 minutes after the injection. There are five major group of reactions occur during contrast examination:

Overdose reactions; infant, adults with acute renal failure, adults with cardiac failure in the beginning stage, and adults with hepatic failure and ascites are particularly at risk receiving an excessive osmotic load.

Anaphylactic reactions; considered allergic-type reactions caused by hypersensitivity to the substance.

Cardiovascular reactions; tend to cause peripheral vasolidation and a decrease in systemic blood pressure which can result in reflex tachycardia because they are related to the effect of the vagus nerve on cardiovascular system, they are referred to as vasovagal or vagal-type reaction. Vasovagal reactions can affect myocardial contractility and cardiac electrophysiology and can ultimately be serious. The most severe of cardiac reaction is cardiac arrest.

Psychogenic reactions; if patient are overanxious, they may respond to the subjective side effects produced as a result of the introduction of the contrast agent with an autonomic response. The response becomes the basis for the adverse reaction. Substances less likely to cross the blood-brain barrier and enter the central nervous system reduce the likelihood of reactions precipitated by this mechanism.

Activation system-triggering reactions; activation of variety system such as complement, coagulation, fibrinolysis and histamine can be triggered as a response to damage to the vascular endothelium at the injection site. These system do not cause the same type of reaction in every patient because of individual variations in the presence and action of inhibitors in the pathways.

Symtoms of rections to contrast agents administered intravenously

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Mild to moderate symptoms

Severe symptoms



Chest pain



Facial swelling

Abdominal pain

Heat sensation


Warm feeling

Vascular pain






Pain at injection site


Loss of consciousness


Cardiac arrest



Tissue necrosis

Sudden drop in blood pressure

The possibility of a reaction should always be anticipated, and proper emergency medication should be available in the special procedure suits. The following is the list of typical emergency equipment:

Oxygen wall system and oxygen tank and mask

Airways(pediatric and adult)

Physiologic saline

Suction apparatus

Emergency drugs(by physician preference)

- hydrocortisone sodium succinate

- metaraminol

- phenylephrine hydrochloride

- diphenylhydramine hydrochloride


Aromatic spirits of ammonia

Syringes and needles for drug injection

Blood pressure device(sphygmomanometer) and stethoscope


The complication is divide into three categories that is those occuring at the puncture site, systemic complication and complication induced by the catheter during the procedure.

Outcomes classification of complication to Arteriographic procedures referred to the effect of the complication on the patient or the level of treatment required

Classification level

Resultant potential outcomes

Minor complications

No therapeutic intervention

Minor therapeutic intervention

Admission for observation-minimum 24 hours

No permenant effect

Major complications

Requires therapeutic intervention

Observation for <48 hours

Major therapeutic intervention

Hospitalization for >48 hours

Permanent effects


*Outcomes from The Society of Interventional Radiology(SIR)

Potential for drug or medication taken by patient to interaction with contrast media must be taking seriously. Example combination of contrast medium with metformin hydrochloride(glucophage taken by patient with type 2 diabetes) increase risk for buildup of lactic acid in the blood. It is referred as lactic acidosis. By natural process by mitochondria, breakdown of sugars and fat to make energy will produce lactic acid(waste product). Normally this lactic acid will be break down into simpler product and is eliminated from the body, but under some circumstances mitochondria is damaged and lactic acid does not break down then it accumulates in the body. This condition will show a symptoms of nausea, muscle weakness, vomiting, weight loss, abdominal pain, dyspnea and cardiac rhythm abnormalities.

Also radiographer must alert to patient creatinine level before the examination. If it wihin normal level under 1.5mg/dL risk for patient to use contast is reduced but if creatinine level above normal limits, suspend or replaced use of metformin.

Complications that occur in puncture site is hematoma, occlusion, and pseudoaneurysm, extravasation of the contrast agent. Risk factor for extravasation is tourniquets does not release during injection, improper use of the automatic injection devices, indwelling catheters in place more than 24 hours, tapes and bandages over intravenous access site that prevent adequate monitoring of injection site, injection into small peripheral veins almostly in the dorsum of foot and hand, multiple attempts to gain vessel access, use of metal needles rather than plastic catheters, use of high osmolarity contrast agents, examination requiring large amounts of contrast agents, abnormalities caused by atherosclerotis vessels, diabetic vascular disease and venous thrombosis, patients with a history of compromised lymphatic or venous drainage, increased risks in children, infants, the elderly, and chronically ill patients.

Specialty contrast agent

Problems occur for magnetic resonance imaging(MRI) procedures because organic iodine compound cannot be contrast agents for this procedure as it only function through absorption of x-ray beam. MRI does not use x-ray to produce image. So, iodinated contrast media only useful in special procedure of radiography and computed tomography(CT). The substance that has been found suitable to becoming contrast media for MRI is gadolinium diethylenetriamine penta-acetic acid (Gd-DTPA) because it is metal chelate. This metal ion have tend to bind wih certain body tissue like in kidneys, liver, heart, brain, bone, spleen and lungs so they can remain in the system for a long period of time. Also it does not cause unneeded side effect and not has shows toxicity to organs system. Primary excretory pathway is via kidneys, 80% Gd-DTPA eliminated in 3hours, 98% eliminated through urination and defecation within 1week of administration.



Intravenous urography(IVU) also known as intravenous pyelogram(IVP) is a radiological procedure used to visualize urinary system by using intravenous contrast agent. Its show the kidneys, ureters and bladder in radiographic film in white and clear image because contrast radiopaque are being used. This will easily for radiographer to anylize and observe any abnormalities in patient urinary system. The intravenous injection of a contrast agent is the mostly ways that was being use to obtain images of the urinary system. Although, ultrasound or computed tomography (CT), are better for some disease processes. When intravenous is injected into blood flow,the kidneys excrete the contrast into the urine and becomes visible when x rayed (radiopaque), creating images of the urinary collection system.

There are procedure name antegrade pyelography differentiates from retrograde pyelography, the contrast agent are injected directly into the lower end of the system that make contrast agents flow backward. That why its name is retrograde. This retrograde pyelography is the most suitable x-ray procedure to observe the lower ureters when kidneys are non-functional.

Nephrotomography or also known as tomographic slices of the kidney, taken by moving x-ray source emit x-ray exposure onto a film and moving in opposite direction. The image upper and lower level of the kidney are blurred that allowing a more detailed image of the kidneys with no over imposed material such as gas or fecal material.

Many available exams suitable for detecting kidney abnormalities, with varying risks and costs:

In a save, simple, quick and inexpensive way to obtain views of internal organ is by using ultrasound. By using ultrasound, renal size can be measured as well as the visualization of abnormalities of cysts, renal calculi, hydronephrosis, and tumors. But small stones in the ureters are not as well visualized and the function of the kidneys cannot be determined.

Then by using nuclear renal scans that rely on the radiation given off by certain atoms (isotopes), that are injected into the bloodstream. It will reach the kidneys, and images are constructed by measuring the radiation emitted. The radiation is not dangerous as standard x-rays. However, this exam has limited applications, including the evaluation of reflux, chronic obstruction, and renal function. It is also used to evaluate high blood pressure that is refractory to treatment, and is commonly used to evaluate the kidney of a renal transplant patient for early rejection where renal artery stenosis is suspected as the cause.

Magnetic resonance imaging (MRI) are mainly using magnetic fields and radio frequency signals and does not use ionizing radiation to create computerized images. This method using magnetic field energy are safe as long as no metal in patient body. It has limited applications and usually is not done for common problems, such as pain and hematuria (blood in the urine). MRI usually is done if other tests are inconclusive. MRA (magnetic resonance angiography) may be done to evaluate the renal arteries, particularly is renal artery stenosis is suspected as a cause of hypertension that is refractory to treatment. MRI need special apparatus and installation and is a very costly exam.

Retrograde pyelography is the most suitable to define problems in the lower part of the ureters, and is the only way to completely opacify the ureters in patients with mulfunction kidney. This exam is performed in an operating room by a urologist. A cystoscope is placed into the bladder and a catheter is placed into each ureter to inject the contrast agent. The advantage of this method is that small stones can be removed immediately by the urologist.

Lastly is computed tomography scans (CT or CAT scans) use a fine beam of x-rays creating images at accurate levels in the body. The information is processed by a computer and imaged onto film using laser printer. Three-dimensional images will be constructed from this technique of imaging. An injection of a contrast agent is required to visualize the kidneys in detail. The CT scan is done without IV contrast to look for stones (calculi). In some centers, this modality has replaced IVPs and ultrasound for this application. Special equipment is necessary and the exam can be costly.


This procedure is being made to investigate of patient urinary incontinence, anuria, hematuria or pyuria not arising from the lower urogenetal tract, suspect urinary bladder disease when bladder cannot be catheterized, abnormal size, shape and position of urinary system,investigation of rretroperitoneal swellings, suspect ureteric disease such as ectopic ureters and identification of kidneys when not visible on plain radiographs.

Example radiograhic image of urinary system with intravenous contrast.


This procedure are also being made to diagnose any abnormalities or disease in urinary system such as chronic pyelonephritia, renal cell carcinoma, kidney stone, polycystic kidneys, transitional cell carcinoma, anatomical variation like horeshoe kidney or duplex collecting system and also obstruction commonly at the pelvic-ureteric junction or PUJ and the vesicoureteric junction or VUJ.


An intravenous urogram is perform to demonstrate the structure and function of the kidneys, ureters, and bladder. Patients that compalin about their abdominal pain at the back may needed to do this exam to rule out kidney stones. Patients with high blood pressure (hypertension) and has bladder infections may also would liketo do intravenous urogram (but hypertension usually is imaged with MRA or nuclear medicine imagery and this exam is done when renal artery stenosis is the suspected cause of refractory hypertension). Hematuria may also be an indication of kidney stones, infection, or tumors. On occasion the exam is planned to evaluate the function of the kidney in a renal transplant patient. The transplanted kidney is located in the iliac fossa, so special films of the pelvis area are done as a replacement for of the normal routine views. The radiographic technologist may also be required to take x-rays in the operating room when a retrograde pyelogram is ordered by a urologist during a C and P (cystoscopy and pyelography).

Emergency patients with blunt abdominal trauma are usually evaluated with a CT scan or occasionally ultrasound instead of an intravenous urogram.


A serious problem of an intravenous urogram is an allergic reaction to the iodine-containing contrast agent. Severe reactions are rare, but can be dramatic and even lethal and dangerous. Because of this, all radiology departments performing this exam are equipped and prepared with emergency drugs and oxygen in the x-ray room itself.


The patient will be asked to change into a hospital gown andtake off any artifact from the region of interest. The x-ray technologist will confirm that the patient has followed the bowel preparation and complete a detailed questionnaire on the recent medical history of the patient. This includes previous contrast reactions, known allergies, current medications and risks of pregnancy. The x-ray technologist will explain the exam in detail to the patient as well as the risks of the contrast material that will be injected intravenously. The patient must sign a consent form before the examination is started to give us permit to do our job to patient. The x-ray technologist will pass on this information to the radiologist who will decide on what type of contrast will be used. Patients who have had an injection with no reaction can be given less expensive iodine-based contrast, whereas patients who take various heart medications or those with known allergies or asthma will be injected with a more expensive contrast agent (known as non-ionic contrast) that has fewer side effects. Some departments use the non-ionic contrast exclusively.

The patient will be instructed to lie supine (face-up) on the x-ray table and a general KUB test will be done. This is an abdominal view of the kidneys, ureter, and bladder used to make sure patient preparation, centering, and the radiographic technique needed to demonstrate all the required structures.

Kidney stones may or may not be visualized on the preliminary film. The x-ray technologist will prepare the required amount of contrast to be used depending on the weight of the patient (1 ml per pound). Normally 50-75 cc of contrast for an average-sized patient. The contrast will be injected all at once (bolus injection) or in some cases, through an intravenous drip. Some radiologists prefer to start an intravenous drip with saline as a precautionary measure while others inject with a small butterfly needle. The needle usually remains in place for 10-15 minutes, in case more contrast is needed or in case drugs need to be administered because of an allergic reaction. Most reactions occur immediately but some can take place 10 or 15 minutes after the injection.

The first film is taken right away after the injection to see a detail of the renal outline (nephrogram). Films are usually taken at five-minute intervals depending on the schedule of the radiologist. Compression may be applied to the lower abdomen with a large band to keep the contrast material stay in the kidneys longer. This will creates a more detailed image of the renal collecting system. When the compression is released after around 10 minutes the contrast material drains quickly and a detailed, filled image of the ureters is obtained. Films is made in the upright or prone (face-down) position may also be planned to improved visualization of the lower ureters. Some departments require routine renal tomographic images to be done as well when the kidneys are well visualized. This allows the kidneys to be seen free of gas or fecal shadows. Sometimes the radiologist requires oblique views of the kidneys or bladder to find out the exact location of calculi (stones). At approximately 20 minutes after the injection a film centered on the bladder may be necessary. The x-ray tube is angled slightly caudad (towards the feet) so that there is no superimposition of the pubic area of the pelvis over the bladder. The films are shown to the radiologist and if no further films are necessary the patient will be asked to void (urinate) and a post-void film will be taken. The exam can take from 30 minutes to one hour depending on the number of films required. If the kidney is obstructed, delayed films may be required to complete the exam.


To obtain the best visualization of the kidneys, ureters, and bladder, the intestines must be free of gas and fecal substance. Most include a laxative such as X-Prep or Dulcolax tablets taken around 4 p.m. the day preceeding the exam. Followed with a light fat-free dinner which includes lean meats, noodles, white rice, bread with no butter, and tea or black coffee. Fluids are permitted until midnight, after which no food or liquid is allowed until after the intravenous urogram is completed. Patients who are diabetic are sometimes done early in the morning to avoid any complications. Patients who have had a previous reaction to a contrast material can be given a series of steroids and antihistamines the day before the exam as well as the morning of the exam. The patient must discuss with their physician before this is administered. In patients with known or suspected renal failure, lab tests, including BUN and creatinine, may be ordered prior to the IVP.


An allergic reaction to the contrast agent is the most important risk, even though kidney damage is also a potential complication. Patients with a possible iodine allergy or a previous reaction to a radiographic contrast agent should inform the x-ray technologist. A detailed history of known allergies, risk of pregnancy, and current medications is required before an intravenous urogram. All radiology departments have consent forms that must be signed by the patient before starting the exam. Emergency equipment and specific drugs such as adrenaline, antihistamines (Benadryl), and atropine are kept in the x-ray room. All radiography technologists must have specific training and education on the various signs and symptoms of an allergic reaction. A mild reaction consists of a skin rash or hives, whereas a more serious reaction includes swelling of the larynx, difficulties in breathing, asthmatic attacks, and a severe drop in blood pressure (hypotension).

Since x-rays are involved during this procedure, there is a minimal risk due to radiation. This exam is not done on pregnant women or women who think they may be pregnant.


A normal intravenous urogram will indicates no visible abnormality in the structure or function of the urinary system. The radiologist looks for a smooth non-lobulated outline of each kidney, no clubbing or other abnormality of the renal calyces (collecting system), no abnormal fluid collection in the kidneys that could suggest as obstruction. The ureters must contain no filling defects (stones) or deviations due to an adjacent tumor. The bladder must have a smooth outline and empty normally as visualized on the post-void film.

Abnormal results include hydronephrosis (distension of the renal pelvis and calices due to obstruction) as a result of tumors or calculi (stones). Cysts or abscesses may also be present in the urinary system. A delay in renal function can also indicate renal disease. An abnormal amount of urine in the bladder after voiding may indicate prostate or bladder problems.

Intravenous urograms are often done on children to rule out a rapid developing tumor in the kidneys, called a Wilm's tumor. Children are also prone to infections of the bladder and kidneys due to urinary reflux (return backflow of urine).

Health care team roles

The x-ray technologist must work in coincidence with the doctors and nurses in making sure the patient has not had a previous allergic reaction to a contrast agent. All hospitals have an emergency team ready to react in such a situation, so the technologist must be aware of the procedure to follow when assistance is necessary due to a severe reaction. Details of patient preparation must also be communicated to the hospital wards. In some hospitals the radiologic technologists are trained to give injections, but if this is not the case nurses may be asked to install an intravenous drip before the patient is brought to the radiology department.

Patient education

The x-ray technologist must explain the risks of an allergic reaction to each patient even though severe reactions are particularly rare due to the advances made in the preparation of contrast agents. The x-ray technologistmust explains to the patient that a warm, flushed feeling or a metallic taste in the mouth are normal reactions in some patients. Breathing instructions are also important since the kidneys change position depending on the phase of respiration and to prevent motion artifacts. Sometimes an emergency patient with renal colic (acute abdominal pain) is asked to urinate through a special filter used to trap small stones. All radiographic technologists must be certified and registered with the American Society of Radiologic Technologists or an equivalent organization. Continued education credits are mandatory to remain registered.



A barium swallow is a radiographic examination for the upper gastrointestinal tract that use barium based as the contrast agent. Upper gastrointestinal tract region is the pharynx (back of the mouth and throat) and the esophagus (hollow tube of muscle extending from below the tongue to the stomach). A barium meal, is a radiographic examination of an upper gastrointestinal tract that is the esophagus, stomach and duodenum are taken after barium sulfate is ingested by a patient. Barium meals are useful in the diagnosis of structural and motility abnormalities of the foregut. This procedure is taken in AP (anteriorposterior) and lateral projection.

Barium solution is a white, dry, chalky, metallic powder that have been mixed with amount of water and must be thick, milkshake-like drink. Barium is a positive contrast agent because of it has high atomic number that make it as a x-ray absorber. It classified as radiopaque and always be used as contrast agent for gastrointestinal tract procedure in radiographic imaging. When swallowed, a barium drink will coats at the wall of pharynx and esophagus so that swallowing motion inside wall lining and size with shape of these organ can be seen white, clear and visible in x-ray film (film receptor). This process shows difference that might not be seen in general or standard x-rays. Barium is used only for diagnostic studies of gastrointestinal tract.

Radiographic image for barium meal can be taken by using cineradiography record whereas continuous dynamic x-ray image is exposed during swallowing and transfer of barium from mouth to stomach. It is suitable for the studies of esophagus condition and gastro-esophagus sphincter. Fluoroscopy is taken when patient drink the barium, x-ray tube is focus on upper gastrointestinal tract of patient. Process of swallowing barium is recorded in video.


Indication for this examination is to find or observe theres any cancers of the head, neck, pharynx, and esophagus tumors. The hiatal hernia mean upward movement of the stomach, either into or alongside the esophagus. The structural problems, such as diverticula, strictures, or polyps (growth). An esophageal varices mean enlarged veins. Muscle disorders such as dysphagia, oesophageal stricture(esophagus become narrow cause difficult in swallowing) or spasms(pharyngeal or esophageal). An achalasia wheres the lower esophageal sphincter muscle does not relax and allow food to pass into the stomach. And also gastroesophageal reflux (abnormal reflux of the stomach acid cause mucosal damage to the esophagus) disease and ulcers. Foreign bodies such as large bolus. Oesophageal atresia is incomplete development of esophagus.


Barium based is insoluble solution that cannot be absorbed by body. So it is toxic to human bodies. It is dangerous for patient that has perforated gastrointestinal tract. Patient that suspected has bowel perforation, bowel obstruction or severe constipation, pregnancy and severe swallowing difficulty such that aspiration (entry of substances into lungs) of barium is likely to occur. As the solution, patient with this problem can use iodinated base contrast medium. It can be absorbed by body and can be easily eliminate through digestive tract.

Patient Care Before the procedure

Explain the procedure to patient and offer the opportunity for patient to ask any questions that might have about the procedure. Patient may asked to sign a consent form that gives your permissions to do the procedure. Read the form carefully and ask questions if something is not clear. If patient is pregnant or suspect that she may be pregnant, patient should notify the physician. Notify your physician if patient is sensitive to or are allergic to any medications aesthetic agents. Notify your physician of all medications and herbal supplements that you patient are taking. Physician may advise patient to withhold certain medications prior to the procedure. Make sure equipment has been prepared for the procedure and sterilized. Make sure emergency troly is prepared. Make sure amount and type of contrast media that being used. Check label of substance before use. Radiographer and doctor that involve in this procedure must wear protective equipment like mask, gloves and apron. Make sure patient is well prepared. Make sure any digital equipment that will be used functioning correctly.

Patient Care During the procedure

Radiographer or doctor need to checking patient identification as the patient is a correct patient that will do this procedure same with identification in application form. Once all required x-rays have been taken, patients will be assisted from the table. Make sure that vein or artery that is administerated is in a correct punture site and entered into it. We must always assist patient whenever they needed. Always observe patient vital sign like heart rate shown by electrocardiogram machine. Give a simple instruction so patient can be easily understand. Never do bad thing to patient and must consent about them. Make sure any elecrical wire is put out from patient movement range and check to avoid any electrical shock from cable and leakage of electrical tube or x-ray tube. When doing procedure, give patient radiation protection such as gonad shield and others. Also comfort patient with good consent and care. Avoid from making patient scared. Always answered when patient ask something. But keep our personal details in a distant secrectly. Once all required x-rays have been taken, assisted patient from the table. Observe patient condition always.

Patient Care After the procedure

Tell the patient that procedure has been finished and assist patient when they need. Tell the patient about contrast media will out from their bodie with feaces. Ask them to inform any abnormal changes to physician or doctor or radiographer. Show the patient place to waiting and collet the report. For outpatient we must arrange next appointment with their doctor. For inpatient, ask for the help of nurse or staff to assist patient to their room or ward.

Preparation For The Procedure

Patient are advise to eat low-fiber diet for 2-3 days before the test. Avoid from taking milk because it can form precipite or fat layer in the stomach. High fiber food like rice and bread are advice to not to take it. Always drink water to clear gastrointestinal tract. Patient may be asked to fast about 8 hours before the procedure, generally start after midnight. Do not smoke before the examination. Do not taking any drug medication accept it is really required and has been informed to physician. If patient have a disease that need constant time to give medication like diabetes mellitus patient, they need special instruction and care. Finishing them early for the procedure is more suitable and good. Ask patient to change to proper attire by wearing a hospital gown. Make sure patient remove any radiopaque thing from the region of interest. Remove any artifact that block the region of interest. Make sure patient sign a consent form that gives permission to do the procedure. If patient is suspected pregnant or pregnant, please follow the advice from doctor or physician.

During The Procedure Of Barium Swallow

Patient will be positioned on an x-ray table that can tilt patient from a horizontal to an upright position. The general x-ray procedure is taken such as chest x-ray and abdominal x-ray before the barium swallow procedure. Patient will also may be asked to change position at intervals during the procedure. The radiologist will ask patient to take a swallow of thickened barium drink. The barium is usually flavoured although it may does not have pleasent taste. As the patient swallow the barium, the radiologist will do it work by take single pictures, a series of x-rays or using fluoroscopy , a video to observe the barium moving through pharynx to stomach. Patient sometime will be asked to hold a breath at certain time during the procedures. Then patient will be asked to swallow a barium "marshmallow", a small pieces of barium-soaked bread that can help to visualize certain structural problems of the esophagus. Once all needed x-rays have been taken, patient will be assisted from the table. Durin this procedure, attention to patient is required because any abnormalities can occur in this time.

After The Procedure Of Barium Swallow

Assist patient out of the room. Ask patient to change to his proper attire and do not forget any of their belongings. Patient could take up again their normal diet and activities after a barium swallow, unless your physician advises you differently. Barium will cause constipation or potential impaction after the procedure if it is not completely eliminated from patient body. Patient is adviced to drink plenty of fluids and eat foods with high fiber to eliminate the barium from the body. Patient also can be give laxatives or cathartic to help to expel the barium out of the body. Because of the barium cannot be absorbed by body but will passes through the entire intestinal tract, your bowel movement will be more lighter in colour until all the barium is secreted out.

Please report to your physician if occur trouble with bowel movements or failure to have a bowel progress . Any pain or distention of the abdomen. Stools that are smaller in diameter than normal.

Hazard And Side Effect Of Barium Swallow

The truth that barium swallow is a safe examination procedure. But because it can form complication in human body it dangerous to us if not folllowing the procedure carefully. Moreover the variety of human body make some of patient give a reaction to this substance. The compli cation of barium swallow is anaphlytic reactions considered as allergic-type reaction caused by the hypersensitivity to the substance. Body will respond to a foreign substance and immune system will make it move to protect body from barium that known as foreign substance. This allergic reaction can cause anaphalytic shock where the cardiac arrest will occur. This will bring death to the patient. After the procedure of barium swallow, patient will fell thirsty and may experience constipitation ifpatient does not drink much of water for a few days. Laxatives is a way for a patient to eliminate barium in a fast way. Patient will feel bloated and discomfort for a few hours after the test.

The symptoms of nausea, vomiting, headache, coughing, flushing, chest pain, abdominal pain, pain at injection site, shivering, itching, edema, warmt feeling and others more is a mild moderate symptoms. Severe symptom for this barium side effect is dyspnea, sudden drop in blood pressure, cardiac arrest, tissue necrosis, loss of consciousness, paresthesias and others. This procedure is very harmful to some of the person.

This procedure is really dangerous for the person that being suspected or have perforated in any of gatrointestinal tract because barium cannot be processes by body. Iodinated based contrast media is being used in this situation because iodine can be easilt dissolve by body and also easily to eliminate.


This contrast medium, barium sulfate helps radiographer to visualizes and differentiate between the soft tissue and the region of the interest in radiographic film. With clear image of region of interest will easily for us to anylize patient problems. The narrowing and irritation of esophagus (the muscular cylindrical tube located between back of thetube and connected to stomach) or the cardiac sphincter. By using this procedures, we can see any disorder process of swallowing or hiatal hernea (upward movements of the stomach, either into or alongside the esophagus). Any structural problem like stricture, polyps or diverticula can be observe easily. The esophageal varice that mean enlarge veins can be seen. Ulcers, achalasia which there the lower esophageal sphincter muscle does not relax and allow food to pass into the stomach and gastroesophagealreflux disease(GERD).



Barium enema is an x-ray examination of colon. Barium is a chalky substance that is put into the colon before the x-rays are taken. The barium coats the inside of the colon, so that a camera can take images of the lining, or mucosa. The doctor may recommend that you get barium enema to check for abnormalities in the colon like colon cancer, polyps which could develop into colon cancer, outpouchings of the colon wall called diverticula. An ulcers or narrowed areas known as strictures and also which may indicate inflammatorybowel disease, other possible causes for unexplained bleeding or a change in bowel habits.

In order to be able to clearly visualize the colon on an x-ray, it must be as empty as possible. In the days leading up to your procedure, your doctor will give you specific directions on emptying your colon. These may include starting a clear liquid diet a day or two prior to the exam by taking laxatives or enemas to clear feces out of the colon. When you arrive at the examination, you will be asked to undress and wears hospital gown then you must lie down on an x-ray table. A lubricated tube will be carefully inserted into your rectum. A bag containing barium will be attached to the tube, and the barium will be allowed to flow into your colon. When enough barium has flowed into your colon, you willl be asked to try very hard not to expel any of it while x-rays are taken. A tiny balloon attached to the tubing that carries the barium may be inflated to prevent any barium from leaking out during the exam. While the x-ray pictures are being taken , you will be asked to roll from side to side, or stand up. This lets the barium flow to different areas so that sufficient x-ray images can be obtained of your entire colon. After many x-ray film is being taken, you willl be given a bed pen to a bathroom and asked to expel as much of the barium as possible. A few more x-rays may be taken after you have passed most of the barium out of your colon.

Risk and benefits of this procedure are dizziness during the course of the exam, infection, accidental tearing called perforation of intestine or rectum, intestinal blockage caused by barium remaining in the colon. Benefits of barium enema is early detction of colon cancer or relatively large polyps, although it is less sensitive then colonoscopy for this purpose. It is less invasive than colonoscopy, which is somewhat riskier and requires sedation.

After your barium enema, you can go home. You won't need to take any special precautions, and will most likely be able to resume your normal diet. Most radiologists instruct patient patients to increase their fluid intake for a period of time to be certain all of the barium is passed. You will likely notice more gas than usual, and see barium in the next several bowel movements that you pass. Once at home, be sure to contact your doctor if you experiences fever or chills, andominal or rectal pain, weakness severe nausea or vomiting, difficulty passing a bowel movement, blood in your stools that was never there before, light-colored stools days after the exams or pencil-thin stools.