Essential Anatomy and Physiology Components

• Mahbubul Alam

Task 1

Most of the nutrients in the feed are large molecules that can not be directly absorbed in the gut due to their size or hydrophobicity. The digestive system is responsible for the reduction in the size of these molecules directly absorbable smaller units and the conversion of hydrophilic molecules with hydrophobic complexes. Proper operation of absorption and transport mechanisms is essential for the delivery of products of digestion in human body cells . An abnormality of one of these systems can cause malnutrition even in the presence of adequate nutrition .

Functions of Digestive System

The task of the digestive system is the physical and chemical breakdown of food. In addition, energy needed by the body , as well as raw materials for growth and repair of body structures come from the food and drink that ingerimos. In the digestion process are the following functions: Test food through the senses of smell and taste, food crushing , dissolution in water, food transport crushed decomposition of food into simple substances with the aid of digestive enzymes, absorption simple substances, and elimination of indigestible residues.

Regulation of digestive functions

Digestive functions traction and secretion are controlled by two main types of regulation: the nervous regulation and hormonal regulation .

Neural Mechanisms

Nervous regulation of motor and secretory phenomena uses two types of neural networks : a local system , the enteric nervous system and the autonomic nervous system (ANS ). Nerve receptors are sensitive to various stimuli : the chemical composition of the chime

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(acidity) , stretching (feeling of fullness ) , etc. . They send impulses to the muscle and secretory cells of the digestive tract via the enteric nervous system consists of the myenteric plexus and submucosal . Neurotransmission is nervous or chemical type ( enkephalins , somatostatin , serotonin, bombesin , neurotensin , etc. . ) .The ANS consists of two contingents of fibers : sympathetic fibers that run along blood vessels, and the parasympathetic fibers of the vagus nerve. These two contingents have antagonistic actions: roughly, sympathetic fibers are inhibitory while the parasympathetic fibers are excitatory .

Structure

Core Structures : Mouth, pharynx , esophagus , stomach … thin intestine , Ano

Associated structures : salivary glands ( three pairs ) , Pancreas , Liver, Gall Bladder ( with their associated ducts) , and Appendix.

Process

The substances that the body needs are absorbed from food , it passes through the digestive system. When chewing food, it is moistened by saliva. As food is sufficiently fragmented and wet mouth are pushed by the tongue into the pharynx and swallowed. The muscles in the walls of the esophagus contract and relax to cause movement in waves, known as peristalsis, which lowers food into the stomach. In this , mixed with acidic juices produced by the wall of the organ. These juices facilitate the fragmentation of food in even smaller particles , the muscles of the stomach wall also contract , and facilitating the greater fragmentation.

Thereafter , they pass into the small intestine where certain products contained in the digestive juices , known enzymes continue the degradation of food in nutritional components which are absorbed by the blood through the walls of the small intestine. Leftover food particles , which are not digested in the small intestine pass into the large intestine where water is absorbed. The remaining food is a partially solid waste is gradually propelled along the large intestine and takes the form of feces reach the rectum. The depositions are stored in the terminal portion of the digestive tract and are then expelled through the anus.

Anatomy

The esophagus is a tube or membranous muscle that extends from the pharynx to the stomach. Incisors to cardia ( portion continues where the esophagus and stomach) there are about 40 cm. Esophagus begins at the neck, chest and traverses into the abdomen through the esophageal orifice diaphragm . Usually it is a virtual cavity ( ie that its walls are joined and only open when the bolus passes ) . Measure reaches the esophagus 25 cm and has a structure consisting of two layers of muscles which allow contraction and relaxation of the esophagus downward . These waves are called peristalsis and is causing the progress of food into the stomach. It’s just a passage of the bolus , and is the union of different holes , oral , nasal , ear and larynx.

Stomach:

The stomach is an organ so that varies depending on the state of repletion (amount of nutritional content present in the gastric cavity) that is usually shaped J. It consists of several parts that are: fundus, body, antrum and pylorus. Its less extensive edge is called the lesser curvature and a larger curvature. The cardia is the boundary between the esophagus and stomach and pylorus is the boundary between the stomach and duodenum. In an individual measures approximately 25cm cardia to the pylorus and the transverse diameter is 12cm. To see what is inside the stomach click here.

Small intestine:

The small intestine begins at the pylorus and ends at the ileoceal valve, which is attached to the first part of the large intestine. Its length is variable and its size gradually decreases from its origin to the ileocecal valve. The duodenum, which is part of the small intestine, is about 25 to 30 cm in length, the small intestine consists of a proximal portion and a distal jejunum or the ileum, the boundary between the two portions is not very apparent. The duodenum joins the jejunum after 30cm from the pylorus. The jejunum-ileum is part of the small intestine that is characterized by relatively fixed ends: The first originates in the duodenum and the second is limited to the ileocecal valve and first portion of the blind. Its size decreases slowly but progressively towards the large intestine. The boundary between the jejunum and ileum is not noticeable. The small intestine villi has numerous surface increasing intestinal absorption of nutrients.

Intestine:

The large intestine . starts from the ileocecal valve in a blind pouch called from where the vermiform appendix and ends at the rectum . From the cecum to the rectum describes a series of curves , forming a frame in the center of the handles are yeyunoíleon . Its length is variable between 120 and 160 cm , and its size gradually reduces , being narrower in the region where it joins portion rectum or rectosigmoid junction, where the diameter is usually not exceed 3 cm , while the blind is 6 or 7 cm.

After the blind , the second portion of the large intestine is called as ascending colon, with a length of 15cm , to give rise to the third portion which is the transverse colon with an average length of 50 cm , resulting in a fourth portion which is the descending colon 10cm in length. Finally differs sigmoid , colon rectum and anus . The rectum is the last part of the digestive tract. It is the continuation of the sigmoid colon and ends up opening up to the outside through the anal opening .

Pancreas:

Gland is intimately related to the duodenum, the excretory duct of the pancreas, which ends meet with the bile through the ampulla of Vater, their secretions areimportant in the digestion of food .

Liver:

The liver is the largest internal organ of the body weighs 1500 grams. It consists of two lobes. The bile ducts are the excretory ducts of the liver , bile for them is driven into the duodenum . normally get two channels: left and right , that converge together to form a single duct . the hepatic duct receives a finer duct, cystic duct coming from the gallbladder housed in the visceral side of liver. Meeting of the cystic duct and the hepatic bile duct , descending duodenum , into which together with the excretory duct of the pancreas is formed. The gallbladder is a reservoir musculomembranous shunted on the main bile duct. It contains about 50-60 cm3 of bile. Is oval or slightly pear-shaped , and its major diameter is about 8 to 10 cm .

Spleen:

The spleen , for its main functions should be considered an organ of the circulatory system. Its size depends on the amount of blood contained therein.

Digestive Physiology

The gastrointestinal tract is responsible for the digestion of the ingested food , so that they can be used by the body . The process of digestion begins in the mouth where food is covered by saliva , crushed and divided by the action of chewing and once formed the bolus swallowed . The stomach is not an essential organ for life, for though his removal in man and animals cause certain digestive disorders, not fundamentally affect health.

In humans , the essential function of the stomach to reduce food to a semi-fluid mass of uniform consistency called chyme , which then passes into the duodenum . The stomach also acts as a temporary reservoir for the acid foods and their secretions , has some antibacterial action.

The chyme passes the pylorus and enters the duodenum intervals where it is transformed by the secretions of the pancreas , small intestine and liver was continued digestion and absorption. Chyme is progressing through the small intestine until it reaches the large intestine.

The ileocecal valve too fast hinders the emptying of the small intestine and prevents reflux of the contents of the large intestine to the small intestine. The main function of the large intestine is the formation , transport and disposal of feces. A very important function is to absorb water. In the cecum and ascending colon faeces are almost liquid and that is where the greatest amount of water and some dissolved substances are absorbed, but also in more distal regions ( rectum and sigmoid colon) liquids are absorbed.

Digestion and absorption

Digestion of food is effected by hydrolysis using digestive enzymes and cofactors such as hydrochloric acid or bile . Cofactors are also involved in the mechanisms of absorption. Enzymes are of 2 types: exoenzymes and endoenzymes.

Digestive enzymes are exoenzymes mainly synthesized by specialized cells of the mouth, stomach , pancreas or small intestine and that are released in the digestive light to catalyze the hydrolysis of the food to the outside of the cell .The enzymes are endoenzymes localized on the membrane lipoproteins digestive mucosal cells . The connection to their substrate therefore when those latter penetrate into the cell. Ingested food are absorbed about 95%. The water , inorganic salts , monosaccharides , vitamins and alcohol are absorbed without change. As against , disaccharides , polysaccharides , lipids and proteins are to be transformed by hydrolysis into simpler components before being absorbed.

Factors influencing the digestion

Psychological factors:

The appearance, smell and taste of food served modifies the emotional climate during the meal which influences the digestion of ingested food. Indeed , salivary secretions , gastric , etc. . and alter motility of the digestive tract . Emotions such as fear , anxiety or anxiety act via the hypothalamus and the autonomic nervous system affect digestion by reducing secretions , inhibition of peristalsis and increased sphincter tone .

Bacterial action .

• The intestinal flora is a complex community with over 100 different species.
• At birth, the gastrointestinal tract is sterile, but many species rapidly colonize the digestive tract.
• Lactobacillus is the main bacteria flora until the child gets a varied diet .
• Then Escherichia coli dominant in the terminal ileum , and the anaerobic flora in the colon appears . However, the number of lactobacilli persist in subjects taking a normal diet.
• In the stomach , hydrochloric acid (HCl ) has a bactericidal action , which destroys most bacteria in the gastric acid chyme . In hyposécrétion gastric cases, bacterial overgrowth can be responsible for gastritis resulting in inflammation of the mucosa.
• In the colon , bacterial action is more intense. It leads to the formation of gas (H2 , CO2 , CH4 , O2, NH3 , etc . ) , Acids ( lactic , acetic , etc . ) , And many other substances ( indoles , phenols , etc. . ) . The smell of feces is related to many of these components.
• The meal ingestion alters the fecal flora in very different ways depending on the individual . The ingestion of carbohydrate fermentation tends to increase while the increase of protein putrefaction .

Effects of food preparation and meal composition .

• Cooking makes them more easily digestible : cooking meat relaxes connective tissue, facilitates chewing making it more accessible to digestive juices tissues.
• A heat load and composition equal meals low volume and more can be better digested than lavish meals .
• The chemical reactions during cooking alter food digestion . Acrolein produced by frying foods at elevated temperature, delays gastric emptying . Instead, meat extract ( bouillon ) stimulate digestion .
• Finally, there is a wide variation within and between individual sensitivity to food, their physical properties (temperature , acidity, etc. . ) That is frequently associated with the state of repletion of the digestive tract .

Task 2

The Endocrine System and Its Working

The endocrine system is a term for all the organs and tissues that produce hormones. They are distributed throughout the body and can show effects over long distances on:

• Growth
• Development
• Functions of many organs
• Coordination of metabolic processes

The endocrine glands are organs, but who have no ducts, because they distribute their products directly into the blood or an autocrine or paracrine effect, however. Therefore, there is at this tissue with a dense network of blood capillaries with windowed endothelium. Exocrine gland secretions free to oppose it with their inner or outer surfaces: on the skin, on the wall of the stomach or in the pancreatic ducts. The hormone-producing tissue can be divided into three groups:

• Purely endocrine glands, used exclusively for the production of hormones;
• Exo-endocrine glands, in addition to the hormones produced other exocrine secretions;
• Certain non-glandular tissue such as the autonomic nerves, which also secrete hormone-like substances =neuro secretion

Location and Function of 3 Endocrine Glands

Thyroid

Developmentally, the thyroid gland goes out of the intestinal epithelium of the pharynx bottom out on the tongue base. This gland stands at the beginning of the development through the ducts thyroglossus still with the floor of the mouth in combination and is located in front of the trachea after a descent. Anatomically, the thyroid gland is composed of two lobes, which are on an isthmus that is sometimes formed as a real pyramidal lobe, in conjunction. Without thyroid hormones cannot live. The thyroid hormonetriiodothyronine (T3) and thyroxin (T4) are iodized. They work in almost all body cells and stimulate there on the energy metabolism. The thyroid itself is in terms of a control system by the hypothalamic hormone TRH (TSH-releasing hormone), and originating from the pituitary TSH (thyroid-stimulating hormone) in their function regulated (Hiller-Sturmhofel, 1998).

Endocrine Pancreas

The pancreas is an exo-endocrine organ by both digestive juices into the duodenum and releases hormones into the bloodstream. The endocrine portion, the islets of Langerhans are localized mainly in the pancreatic and stand out due to their brighter appearance. They secrete their secretions directly into the bloodstream. A distinction is to effect different types of cells:

• B cells: 60-80%, are used to produce insulin
• A cells: approximately 20%, and are therefore intended to antagonist to insulin
• D cells: about 2% serve to have an inhibitory effect on the A-and B-cells as well as on the exocrine pancreas.
• PP cells (pancreatic polypeptide): ~1-2% and inhibit pancreatic exocrine

These islands consist of a net-like organization of several thousand epithelial cells arranged in groups and are crossed by numerous capillaries with windowed endothelium (Carter, n.d.)

Pituitary

The pituitary gland is located at the underside of the brain and is composed of three parts. In contrast, the anterior pituitary produces own hormones. The activity of its cells is determined by complex humeral and neural mechanisms regulated (= control hormones). It is above all the hypothalamic releasing – and release-inhibiting hormones that play an important role (Drake, 2010)