Erbaet al., examined the effectof two cups of green tea to a controlled diet in a group of healthy adults, compared with group following the same controlled diet but not taking green tea. Antioxidant status and lipid profile in plasma were measured at the start and at the end of experiment. Intake of green tea resulted in significant rise in plasma antioxidant activity, significant fall in plasma peroxides level and induced DNA oxidative damage in lymphocytes, a reasonable significant decrease occurein LDL cholesterol with respect to control.
Zaveri, (2005) reported that consuming a lot of cups of green tea daily is beneficial. Numerous epidemiological studies have revealed valuable effects of green tea in cancer, cardiac, and neural diseases. The health profits associated with green tea intake have also been validated in animal studies of cancer chemoprevention, artherosclerosis, Parkinson's disease, Alzheimer's disease, and other aging associated illnesses. By means of a cancer chemo protective or for other health paybacks green tea use has been confounded by the low oral bioavailability of its most dynamic poly phenolic catechins, epigallocatechin-3-gallate (EGCG). Dosage-associated alterations in the effects of EGCG in cancer, neurodegenerative and cardiac diseases, as well as differences between dosages used in vitro studies and in vivo effects of green tea catechins in humans were observed.
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. Beneficial effect of green tea intake on atherosclerosis was examined by Ohmoriet al., (2005). Green tea has revealed to hinder LDL oxidation, platelet aggregation, and matrix metallo proteinases activities in vitro. Serum malondialdehydeLDL concentrations and urine 8-epi-prostaglandin was measured in healthy non-smokers men, they were provided with seven cups of water daily for two weeks and seven cups of green tea for next two weeks. It was proved that daily intake of green tea sifnificantly lowers the serum malondialdehydeLDL concentration, but had no significant effects on platelet aggregation, platelet production or plasma metallo proteinases concentrations. And green tea intake also preventLDL oxidation in vivo.
Cheng, (2006) discussed the effect of green tea on cardiac diseases, atherosclerosis, diabetes mellitus, hypertension, obesity, metabolic syndrome and compare the green tea with black tea. Tea is one of the most extensively used drinks worldwide, besides water. On the basis of fermentation, tea can be classified as green tea (not fermented), oolong tea (semi fermented) and black tea (fully fermented). Due to increased amount of catechin, epigallocatechingallate (EGCG), green tea has been considered better than black tea in terms of antioxidant action. Lower ranks of catechins to a higher level in black tea as compared to other teas, are owed to the procedures involved in the production of black tea. The flavonoids of green tea have beneficial effect on cardiac diseases, not only due to antioxidant, anti-inflammatory, anti-thrombogenic actions but also betterment of coronary flow velocity fallback.
Kuriyamaet al., (2006) performed an experiment on healthy adults which were not previously suffering from cardiovascular diseases or cancer to examine the associations between green tea intake and mortality due to cardiovascular diseases, cancer. Green tea intake was inversely associated with mortality due to all causes and due to cardiovascular diseases. In women the inverse relation with mortality was stouter. In men, the ratio of mortality due to all causes was linked with different levels of green tea intake. The inverse relationship with cardiac disease mortality was observed, while no inverse relation with cancer mortality was observed. Among the types of cardiac disease mortality, the strongest inverse relationship was detected for stroke mortality.
Cabreraet al., (2006) reviewed that tea is the most usually taken beverage besides water, worldwide. Green tea is a non-fermented tea, and encloses more catechins, as compared to oolong and black tea. Catechins are strong anti-oxidants, it contains micronutrients that increases the antioxidant power. Green tea has been deliberated as a beneficial drink by Chinese, since ancient time. According to current human researches green tea can help to decrease the hazard of cardiac disease and to the promotion of oral health and some types of cancer, as well as other physiological roles such as anti-hypertensive effect, obesity control, antibacterial and anti-viral activity, anti-fibrotic activities, rise in bone mineralization, and neuro-defensive power. Green tea has been included in assembly of drinks with functional properties, due to increase attention in health pay properties of green tea.
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Koo and Noh., (2007) supported from in vitro and in vivo researches that green teacatechins hinder the gastric absorption of dietary lipids. In vitro researches specify that green tea catechins, epigallocatechin-3-gallate, affect with the emulsification, digestion and solubility of lipids, dangerous stages involved in the gastric absorption of dietary fat, lipids, and cholesterol. Animal and epidemiological researches recommend that green tea catechins may decrease the hazard of cardiac diseases. Green tea health benefits have been credited to its antioxidant and anti-inflammatory properties; though, significant proof recommends that green teacatechins may decrease the hazard of cardiac disease by decreasing the plasma levels of cholesterol and triglyceride. Green teacatechins might be used as safe and active lipid decreasing beneficial agents.
Khan and Mukhtar., (2007) reported that even though health paybacks have been credited to tea, particularly, green tea intake since many years, scientific inquiries of tea and its ingredients have been ongoing for at least three eras. Tea prepared from the leaves of the ââ‚¬ËœCamellia sinensisââ‚¬â„¢ has been consumed for almost fifty centuries. Tea, green or black, is the most extensively cosumed drink worldwide, now a days. In vitro and animal researches deliver durable indication that polyphenols extracted from tea may retain the bio-ability to alter the disease occurrence of many progressive diseases. Green tea polyphenol, epigallocatechin-3-gallete, has been exposed to be accountable for most of the health sup, as compared to polyphenols of other teas. In a diversity of animal models of cancer, tea has been revealed to hinder tumor formation.
Wolfram, (2007) suggested that in numerous epidemiological researches dose-response interactions have designated that by regular intake of five to six or more cups of green tea a day, distinct cardiac and metabolic health paybacks can be acquired. Intervention researches using analogous quantities of green tea, comprising 200ââ‚¬"300 mg of EGCG, have revealed its effectiveness for sustaining cardiac and metabolic health. Various in vivo studies indicate that green tea and EGCG employ cardiovascular and metabolic paybacks. Hence, green tea and EGCG can be considered as food constituents valuable for the conservation of cardiovascular and metabolic health.
Nagao et al., (2007) inspected the effect of green tea catechins in decreasing body fat and hazard of cardiac diseases in arbitrarily selected Japanese males and females. The persons were given green tea catechins with usual dietary intake and normal physical movement. The unbroken intake of green tea rich in catechins resulted in decrease in body fat, LDL cholesterol and blood pressure, signifying that green tea rich in catechin is hellpful in retarding life related diseases.
Tinahoneset al., (2008) studied to determine the effect of a green tea on vascular function and lipid peroxidation. The research was conducted with healthy females, which were not taking medication previously. The intake of green tea was linked with a significant decrease in the amount of oxidized LDL. Hence it was concluded that green tea intake by females results in changes in vascular function and a significant reduction in serum LDL oxidation.
Chackoet al., (2010)for a varied diversity of conditions, inspected the health profits of green tea, together with many types of cancer, hepatic and cardiac diseases. Many of these valuable effects of green tea are associated to its catechins, mainly (-)-epigallocatechin-3-gallate, evidenced through in vitro, animal and human studies on the basic biological activities of green tea catechins. Against high-fat diet-prompted obesity and type II diabetes continuing intake of green tea catechins could be valuable and could decrease the hazard of cardiac disease.
Mineharuet al., (2011) investigated the association between the intakes of green tea, oolong tea, black tea and coffee, and hazard of mortality from cardiac diseases, entities of specific age group not previously suffering from cardiovascular diseases and cancer at initial phase were monitored. The everyday intake of these drinks was evaluated by surveys. Green tea, oolong tea, black tea and coffee intake were connected through a lesser hazard of mortality from cardiac diseases.
Zhenget al., (2011) identified the effect of green tea on total cholesterol, LDL cholesterol, and HDL cholesterol. They identified relevant trials of green tea drinks and extracts on lipid profiles in adults. By using random-effects models weighted mean differences were calculated for clear fluctuations in lipid concentrations. The investigation of studies revealed that the intake of green tea beverages resulted in noteworthy decrease in serum total cholesterol and LDL-cholesterol concentrations, but no influence on HDL cholesterol was detected. Analyses revealed that these alterations were not affected by the dose of green tea, type of intervention, study length, individual health status, or value of the conducted study.
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