Custom Health Essays
Health Custom Essays: Spinal Cord Trauma
Loss of sensory and motor function below the injury site is caused by trauma to the spinal cord. Appproximately 10,000 people experience serious spinal cord injury each year. There are four general types of spinal cord injury, cord maceration and laceration, contusion and solid core injury. There are three phases of SCI response that occur after injury:the acute, secondary, and chronic. The most immediate concern is patient stabilization. Additionally interventions may be instituted in an effort to improve function and outcome.
Through health, and future development one day there will be hope for recovery from the spinal cord injury. Loss of sensory and motor function below the injury site is caused by trauma to the spinal cord. As indicated by Huether & McCance (2008) normal activity of the spinal cord cells at and below the level of injury ceases due to loss of continuous tonic discharge from the brain and brain stem.
Depending on the extent of the injury reflex function below the point of injury may be completely lost. This involves all skeletal muscles, bladder, bowel, sexual function and autonomic control. In the past hope for recovery has been minimal. With medical advancements and better understanding today hope for recovery is better but still
Health Custom Essays: Drug Absorbed Administration
The oral route is still the most desired route for the administration of medicinal products1 due to the ease and lack of inconvenience associated with this administration route, in comparison to others such as the pulmonary route or the more invasive intravenous route. The pharmaceutical industry has developed considerably over the past 40 years with respect to the rate at which new chemical entities are being discovered.
This increased rate is primarily due to the invention of high throughput screening, but there is no correlation between the rate of synthesis of these novel compounds and the release of new drugs on the market due to the high failure rate during the development process.
In order to minimise cost and resources associated with this loss, effective screening methods for both pharmacological action and bioavailability have to be used. The most important process that influences bioavailability of the drug is absorption and the necessity of creating and using suitable models that can predict the in vivo absorption profile of a drug is absolutely critical in achieving the desired reduction in cost associated with the pharmaceutical development process.
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